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Pomalidomide-PEG2-azide

  Cat. No.:  DC67980   Featured
Chemical Structure
2267306-14-7
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More than 5000 active chemicals with high quality for research!
Field of application
Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. Pomalidomide-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cas No.: 2267306-14-7
Chemical Name: Pomalidomide-PEG2-azide
Synonyms: 2-[2-(2-Azidoethoxy)ethoxy]-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]acetamide;Pomalidomide-PEG2-azide;2267306-14-7;DA-56989;2-[2-(2-azidoethoxy)ethoxy]-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]acetamide;E83732;MS-28004;HY-137537;CS-0139831;2-(2-(2-AZIDOETHOXY)ETHOXY)-N-(2-(2,6-DIOXOPIPERIDIN-3-YL)-1,3-DIOXOISOINDOLIN-4-YL)ACETAMIDE;SCHEMBL23578881;Pomalidomide-PEG2-N3;AKOS040757513
SMILES: O=C1C(CCC(N1)=O)N1C(C2C=CC=C(C=2C1=O)NC(COCCOCCN=[N+]=[N-])=O)=O
Formula: C19H20N6O7
M.Wt: 444.398103713989
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC67980 Pomalidomide-PEG2-azide Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. Pomalidomide-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
DC67845 N-Me-Thalidomide 4-fluoride N-Me-Thalidomide 4-fluoride is a ligand for E3 ligase, used for the synthesis of Anti-inflammatory agent 70 .
DC67844 CRBN ligand-880 CRBN ligand-880 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-880 can be linked to a target protein ligand via a linker to form a PROTAC.
DC67843 6-hydroxy-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
DC67842 Tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperazine-1-carboxylate
DC67841 Boc-NH-PEG4 Boc-NH-PEG4 (PROTAC Linker 12) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
DC67840 tert-Butyl (6-hydroxyhexyl)carbamate tert-Butyl (6-hydroxyhexyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
DC67839 tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate (Standard) tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate (Standard) is the analytical standard of tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate. This product is intended for research and analytical applications.
DC67838 3-amino-1-methylpiperidine-2,6-dione hydrochloride
DC67837 (S)-3-Amino-piperidine-2,6-dione hydrochloride
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