Cas No.: | 833481-73-5 |
Chemical Name: | 2OH-Bnpp1 |
Synonyms: | Phenol,2-[[4-amino-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]methyl]-;BCP29885;2-((4-amino-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenol |
SMILES: | OC1C=CC=CC=1CC1C2=C(N)N=CN=C2N(C(C)(C)C)N=1 |
Formula: | C16H19N5O |
M.Wt: | 297.354962587357 |
Purity: | >98% |
Sotrage: | 0°C (short term), -20°C (long term), desiccated |
Publication: | [1]. Nyati S, et al. The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Sci Signal. 2015 Jan 6;8(358):ra1. |
Description: | 2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer. |
References: | [1]. Nyati S, et al. The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Sci Signal. 2015 Jan 6;8(358):ra1. |