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(3S,4S)-PF-06459988

  Cat. No.:  DC46168  
Chemical Structure
1858291-14-1
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More than 5000 active chemicals with high quality for research!
Field of application
(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1858291-14-1
Chemical Name: (3S,4S)-PF-06459988
SMILES: C=CC(N1C[C@@H](COC2=C3C(NC=C3Cl)=NC(NC4=CN(C)N=C4)=N2)[C@H](OC)C1)=O
Formula: C19H22ClN7O3
M.Wt: 431.88
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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