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AG-126

  Cat. No.:  DC11272   Featured
Chemical Structure
118409-62-4
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More than 5000 active chemicals with high quality for research!
Field of application
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 118409-62-4
Synonyms: AG 126; AG126; AG-126
SMILES: N#C/C(C#N)=C/C1=CC=C([N+]([O-])=O)C(O)=C1
Formula: C10H5N3O3
M.Wt: 215.03
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: AG126 is a tyrosine kinase inhibitor which can prevent the activation of mitogen-activated protein kinase p42MAPK (ERK2).
Target: ERK2
References: [1]. Cuzzocrea S, et al. The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation. Am J Pathol. 2000 Jul;157(1):145-58.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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