Cas No.: | 520-36-5 |
Chemical Name: | 4′,5,7-Trihydroxyflavone 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone |
SMILES: | O=C1C(C(O)=CC(O)=C2)=C2OC(C3=CC=C(O)C=C3)=C1 |
Formula: | C15H10O5 |
M.Wt: | 270.24 |
Purity: | >98%, Standard References Grade |
Sotrage: | 4°C for 1 year, -20°C for more than 2 years |
Description: | A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53.Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C1 and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication. |