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BOS172722

  Cat. No.:  DC12405   Featured
Chemical Structure
1578245-44-9
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More than 5000 active chemicals with high quality for research!
Field of application
BOS172722 (BOS-172722) is a potent, selective MPS1 kinase inhibitor with biochemical IC50 of 11 nM, 100-fold selectivity over CDK2.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1578245-44-9
Chemical Name: N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine
Synonyms: BOS-172722;BOS 172722
SMILES: C(NC1=CC=C(C2N(C)C=NN=2)C=C1OCC)1=NC=C2C=C(C)N=C(NCC(C)(C)C)C2=N1
Formula: C24H30N8O
M.Wt: 446.559
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM.
In Vitro: BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM. BOS-172722 also has potential for the treatment of various forms of breast cancer[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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