C7280948|cas 587850-67-7|DC Chemicals|Price|Buy

Cas No.:	587850-67-7
Chemical Name:	4-amino-N-phenethylbenzenesulfonamide
Synonyms:	C 7280948,C-7280948
SMILES:	Nc1ccc(cc1)S(=O)(=O)NCCc2ccccc2
Formula:	C₁₄H₁₆N₂O₂S
M.Wt:	276.35
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	C-7280948 is a PRMT1 inhibitor.
Target:	PRMT1
In Vitro:	Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs). The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer. C-7280948 is a inhibitor, which is available for PRMT1.
References:	[1]. Bissinger EM, et al. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bioorg Med Chem. 2011 Jun 15;19(12):3717-3731.

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