CCS-1477|CAS 2222941-37-7|DC Chemicals

Cas No.:	2222941-37-7
Chemical Name:	Inobrodib
Synonyms:	CBP-IN-1;(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1r,4S)-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one;CBP/p300-IN-4;Inobrodib;2-Piperidinone, 1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-, (6S)-;D12394;SCHEMBL20094038;GTPL13063;Ccs 1477;SCHEMBL22134021;BDBM50602864;WHO 11833;Inobrodib [INN];CCS-1477 (CBP-IN-1);(6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one;SCHEMBL21515367;AKOS040732748;MS-29881;CCS-1477(CBP-IN-1)?;G16679;Inobrodib (USAN);NSC818619;CCS1477;CBP-IN-1;CBP/p300-IN-4;EX-A3687;2222941-37-7;SCHEMBL23433835;CHEMBL4785363;NSC-818619;BW5QA5GEW7;(6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one;(S)-1-(3,4-difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-(4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one;HY-111784;DA-71991;CBP-?IN-?1;(6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1r,4r)-4-methoxycyclohexyl]-1,3-benzodiazol-2-yl]piperidin-2-one;CCS-1477;CCS1477; Inobrodib;CCS1477;UNII-BW5QA5GEW7;(6S)-1-(3,4-difluorophenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]piperidin-2-one;s9667;(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-(trans-4-methoxycyclohexyl)-1H-benzo[d]imidazol-2-yl)piperidin-2-one;CCS 1477 [WHO-DD];GLXC-26849;2-Piperidinone, 1-(3,4-difluorophenyl)-6-(5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl)-, (6S)-;JHL;CS-0091862;(S)-1-(3,4-Difluorophenyl)-6-(5-(3,5-dimethylisoxazol-4-yl)-1-((1R,4S)-4-methoxycyclohexyl)-1H-benzo(d)imidazol-2-yl)piperidin-2-one;Inobrodib [USAN];Inobrodib [USAN:INN];P300/cbp bromodomain inhibitor CCS1477
SMILES:	FC1=C(C([H])=C([H])C(=C1[H])N1C(C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC2C([H])=C(C3C(C([H])([H])[H])=NOC=3C([H])([H])[H])C([H])=C([H])C=2N1C1([H])C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])OC([H])([H])[H])=O)F
Formula:	C₃₀H₃₂F₂N₄O₃
M.Wt:	534.5969
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	CCS1477: A Novel Small Molecule Inhibitor of p300/CBP Bromodomain for the Treatment of Acute Myeloid Leukaemia and Multiple Myeloma.---Blood (2019) 134 (Supplement_1): 2560.

Description:	CCS-1477(CBP-IN-1) is a potent p300/CBP bromodomain inhibitor[1].
Target:	p300/CBP[1]
References:	[1]. Neil Anthony Pegg, et al. Pharmaceutical compounds. WO2018073586A1.

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CCS-1477(CBP-IN-1)