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Home > Molecular Glues

Avadomide hydrochloride

  Cat. No.:  DC31426   Featured
Chemical Structure
1398053-45-6
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More than 5000 active chemicals with high quality for research!
Field of application
Avadomide hydrochloride (CC-122 hydrochloride), the salt form of Avadomide (HY-100507), is an orally bioavailable cereblon-targeting agent that exerts potent antitumor and immunomodulatory effects. By modulating cereblon E3 ubiquitin ligase activity, this compound inhibits the NF-κB signaling pathway and induces G1 phase cell cycle arrest, ultimately triggering apoptosis in PDAC cancer cells.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1398053-45-6
Chemical Name: Avadomide hydrochloride
Synonyms: Avadomide HCl;Avadomide hydrochloride;Avadomide hydrochloride (USAN);Avadomide hydrochloride [USAN];3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione hydrochloride;D11133;(3RS)-3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione monohydrochloride;2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-, hydrochloride (1:1)
SMILES: Cl.O=C1C(CCC(N1)=O)N1C(C2C(=CC=CC=2N=C1C)N)=O
Formula: C14H15ClN4O3
M.Wt: 322.746901750565
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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