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CFI-400437

  Cat. No.:  DC10069   Featured
Chemical Structure
1247000-76-5
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More than 5000 active chemicals with high quality for research!
Field of application
CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1247000-76-5
Chemical Name: CFI-400437 HCl
Synonyms: CFI 400437,CFI400437
SMILES: CN1CCN(CC1)C2=NC=C(C=C2)/C=C/C3=NNC4=C3C=CC(=C4)/C=C/5\C6=C(C=CC(=C6)OC)NC5=O.Cl.Cl
Formula: C29H30Cl2N6O2
M.Wt: 565.5
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM).
In Vitro: CFI-400437 is potent against PLK4 (IC50 = 0.6 nM) and selective against other members of the PLK family (>10 uM). Against a broad panel of kinases, only a small subset is significantly inhibited. CFI-400437 is a potent inhibitor of MCF-7, MDA-MB-468, and MDA-MB-231 cell growth and very effective in a mouse xenograft model of tumor growth
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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