CID 1375606|CAS 313493-80-0|DC Chemicals

Cas No.:	313493-80-0
Chemical Name:	CID 1375606
Synonyms:	CID 1375606；CID-1375606；CID1375606
SMILES:	O=C(NC1=CC=C(C(NC2=CC=CC=C2)=O)C=C1)C3=CC=C(Cl)C=C3Cl
Formula:	C₂₀H₁₄Cl₂N₂O₂
M.Wt:	385.24
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.
Target:	GPR 27[1].
In Vitro:	CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].
References:	[1]. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608.

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