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Leelamine hydrochloride

  Cat. No.:  DC11131  
Chemical Structure
16496-99-4
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More than 5000 active chemicals with high quality for research!
Field of application
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 16496-99-4
Chemical Name: ((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methanamine hydrochloride
Synonyms: Dehydroabietylamine HCl; Leelamine HCl; Leelamine hydrochloride; Leelamine; NSC-2955; NSC 2955; NSC2955;
SMILES: [C@](C)(CN)1[C@@]([H])2[C@](C)(C3=C(CC2)C=C(C(C)C)C=C3)CCC1.[H]Cl
Formula: C20H32ClN
M.Wt: 321.933
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC47001 Rezvilutamide Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer.
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DC45606 CLP-3094 CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). CLP-3094 inhibits AR transcriptional activity (IC50=4 μM). CLP-3094 is a selective, potent GPR142 antagonist.
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DC41093 Apalutamide D4 Apalutamide D4 (ARN-509 D4) is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM.
DC40448 Androgen receptor antagonist 1 Androgen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively.
DC40171 (R)-UT-155 (R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer.
DC28943 11-Ketodihydrotestosterone 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells.
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