BLU-782

Cas No.:	2141955-96-4
Chemical Name:	[(3R)-Oxolan-3-yl] 4-[6-[5-(4-ethoxy-1-propan-2-ylpiperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazine-1-carboxylate
Synonyms:	ALK2-IN-1;(R)-Tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate;BLU782;[(3R)-Oxolan-3-yl] 4-[6-[5-(4-ethoxy-1-propan-2-ylpiperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazi
SMILES:	O(C([H])([H])C([H])([H])[H])C1(C2=C([H])N=C(C3=C([H])N4C(=C3[H])C(=C([H])C([H])=N4)N3C([H])([H])C([H])([H])N(C(=O)O[C@@]4([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H]
Formula:	C31H42N6O4
M.Wt:	562.703
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ALK2-IN-1 is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC50 of <10 nM[1].