PF-4778574|PF4778574;PF 4778574

Cas No.:	1219633-99-4
Chemical Name:	N-{(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl}propane-2-sulfonamide
Synonyms:	PF4778574;PF 4778574
SMILES:	CC(S(N[C@@H]1CCOC[C@H]1C1=CC=C(C2SC(C#N)=CC=2)C=C1)(=O)=O)C
Formula:	C₁₉H₂₂N₂O₃S₂
M.Wt:	390.516
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PF-4778574 (PF4778574) is a brain penetrant, positive allosteric modulator (potentiator) of AMPA receptor with Ki of 85 nM, increases S-AMPA-evoked responses in rat primary cortical neurons with EC50 of 45-919 nM; robustly ameliorates ketamine-induced working memory impairments in vivo.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
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