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AL-335

  Cat. No.:  DC20260   Featured
Chemical Structure
1613589-09-5
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More than 5000 active chemicals with high quality for research!
Field of application
AL-335 is a potent inhibitor of hepatitis C virus (HCV) NS5B polymerase with IE50 values as low as 70 nM. AL-335 is potentially useful for the Treatment of Hepatitis C Infection. AL-335 demonstrated high levels of the nucleoside triphosphate in vitro in primary human hepatocytes and Huh-7 cells as well as in dog liver following a single oral dose. AL-335 was selected for the clinical development where it showed promising results in phase 1 and 2 trials.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1613589-09-5
Chemical Name: Adafosbuvir
Synonyms: Adafosbuvir
SMILES: C[C@]1([C@@H]([C@@](F)(COP(=O)(N[C@@H](C)C(=O)OC(C)C)OC2C=CC=CC=2)O[C@H]1N1C=CC(=O)NC1=O)O)O
Formula: C22H29FN3O10P
M.Wt: 545.451930761337
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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