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CDK9-IN-8

  Cat. No.:  DC20335   Featured
Chemical Structure
2105956-51-0
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More than 5000 active chemicals with high quality for research!
Field of application
CDK9-IN-8 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2105956-51-0
Chemical Name: Cdk9-IN-8
Synonyms: CDK9-IN-8;1-N-[4-[[7-cyclopentyl-6-(dimethylcarbamoyl)pyrrolo[2,3-d]pyrimidin-2-yl]amino]phenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;BDBM50268674
SMILES: FC1C=CC(=CC=1)NC(C1(C(NC2C=CC(=CC=2)NC2=NC=C3C=C(C(N(C)C)=O)N(C3=N2)C2CCCC2)=O)CC1)=O
Formula: C31H32FN7O3
M.Wt: 569.629289627075
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CDK9-IN-8 is a highly effective and selective CDK9 inhibitor with an IC50 of 12 nM.
Target: CDK9:12 nM (IC50)
References: [1]. Li Y, et al. Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3231-3237.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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