Cas No.: | 614-05-1 |
Chemical Name: | 3-((4-hydroxy-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride hydrochloride |
SMILES: | Cl.[Cl-].OCCC1SC=[N+](CC2=CN=C(C)NC2=O)C=1C |
Formula: | C12H17Cl2N3O2S |
M.Wt: | 338.247 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Oxythiamine chloride is a small molecule transketolase inhibitor with Kd of 33 nM, shows functional assay of human transketolase inhibition in HCT-116 cells with EC50 of 26 nM; Oxythiamine induces G1 arrest in Ehrlich’s ascites tumor cells implanted in mice. |