AZ13705339|AZ 13705339

Cas No.:	2016806-57-6
Chemical Name:	AZ13705339
Synonyms:	AZ13705339;2-[[[2-[[3-(Ethylsulfonyl)-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-fluoro-4-pyrimidinyl][5-(hydroxymethyl)-2-methylphenyl]amino]methyl]benzonitrile;AZ13705339 (AZ 13705339);AZ 13705339;2016806-57-6;AKOS040747884;CHEMBL3923175;MS-30846;BDBM50201641;DA-71176;CS-0079683;G79584;2-(((2-((3-(ethylsulfonyl)-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-fluoropyrimidin-4-yl)(5-(hydroxymethyl)-2-methylphenyl)amino)methyl)benzonitrile;HY-120940;2-(((2-(3-(Ethylsulfonyl)-4-(4-methylpiperazin-1-yl)phenylamino)-5-fluoropyrimidin-4-yl)(5-(hydroxymethyl)-2-methylphenyl)amino)methyl)benzonitrile;2-[[N-[2-[3-ethylsulfonyl-4-(4-methylpiperazin-1-yl)anilino]-5-fluoropyrimidin-4-yl]-5-(hydroxymethyl)-2-methylanilino]methyl]benzonitrile;GLXC-20355
SMILES:	C(#N)C1=CC=CC=C1CN(C1C(F)=CN=C(NC2=CC=C(N3CCN(C)CC3)C(S(CC)(=O)=O)=C2)N=1)C1=CC(CO)=CC=C1C
Formula:	C₃₃H₃₆FN₇O₃S
M.Wt:	629.747448921204
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

AZ13705339 is a potent, selective PAK1 inhibitor with IC50 of 0.33 nM, displays 14-, 470-, 4100- and 2600-fold selectivity over Src, FGFR1, KDR and PAK4; inhibits cellular pPAK1 inhibition in MCF10A cell line with IC50 of 59 nM.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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