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BI-1347

  Cat. No.:  DC20775   Featured
Chemical Structure
2163056-91-3
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More than 5000 active chemicals with high quality for research!
Field of application
BI-1347 is a potent, selective inhibitor of CDK8/cyclinC with IC50 of 1 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2163056-91-3
Chemical Name: 2-(4-(4-(isoquinolin-4-yl)phenyl)-1H-pyrazol-1-yl)-N,N-dimethylacetamide
Synonyms: BI1347,BI 1347
SMILES: CN(C)C(=O)CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC4=CC=CC=C43
Formula: C22H20N4O
M.Wt: 356.429
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: BI-1347 is a potent CDK8 inhibitor extracted from patent WO2017202719A1, product I-003, has an IC50 of 1.1 nM[1].
Target: IC50: 1.1 nM (CDK8)[1]
References: [1]. Harald Engelhardt, et al. New phenylpyrazolylacetamide compounds and derivatives as cdk8/cdk19 inhibitors.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
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