Cas No.: | 1821669-43-5 |
Chemical Name: | 4-Acetylamino-N-(2-amino-5-pyridin-4-yl-phenyl)-benzamide |
Synonyms: | BRD2492;4-Acetylamino-N-(2-amino-5-pyridin-4-yl-phenyl)-benzamide;BDBM178095 |
SMILES: | O=C(C1C=CC(=CC=1)NC(C)=O)NC1C(=CC=C(C2C=CN=CC=2)C=1)N |
Formula: | C20H18N4O2 |
M.Wt: | 346.382524013519 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation. |