Cas No.: | 1621694-21-0 |
Chemical Name: | TD-1 |
SMILES: | O1CC(C2NC(=NN=2)SSC2NC(=NN=2)C2COC3C(=CC=CC=3)O2)OC2C1=CC=CC=2 |
Formula: | C20H16N6O4S2 |
M.Wt: | 468.508840560913 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling; increases the oxygen affinity of sickle hemoglobin and inhibits in vitro hypoxia-induced sickling of red blood cells in patients with sickle cell disease without causing hemolysis; a novel lead molecule for the treatment of patients with sickle cell disease. |