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Nidufexor（LMB-763）

  Cat. No.:  DC21243   Featured
Chemical Structure
1773489-72-7
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More than 5000 active chemicals with high quality for research!
Field of application
Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1773489-72-7
Chemical Name: 4-[(N-benzyl-8-chloro-1-methyl-1,4-dihydro[1]benzopyrano[4,3-c]pyrazole-3-carboxamido)methyl]benzoic acid
Synonyms: LMB763;LMB-763
SMILES: O=C(O)C1=CC=C(CN(CC2=CC=CC=C2)C(C3=NN(C)C4=C3COC5=CC=C(Cl)C=C54)=O)C=C1
Formula: C27H22ClN3O4
M.Wt: 487.94
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Chianelli D, et al. Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis. J Med Chem. 2020 Apr 23;63(8):3868-3880.
Description: Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders.
Target: FXR[1]
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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