MMV390048|CAS 1314883-11-8|DC Chemicals

Cas No.:	1314883-11-8
Chemical Name:	MMV390048
Synonyms:	MMV-390048;MMV390048;GLXC-03743;DA-55583;SB17070;0Z5T00JJ10;AS-35285;SCHEMBL2225969;5-(4-(Methylsulfonyl)phenyl)-6'-(trifluoromethyl)-3,3'-bipyridine-2-amine;3-(2-(TRIFLUOROMETHYL)PYRIDIN-5-YL)-5-(4-(METHYLSULFONYL)-PHENYL)PYRIDIN-2-AMINE;5-(4-methanesulfonylphenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine;AKOS030628490;NCGC00345613-01;J3.367.891F;BDBM50385912;1314883-11-8;(3,3'-Bipyridin)-2-amine, 5-(4-(methylsulfonyl)phenyl)-6'-(trifluoromethyl)-;3-(2-(Trifluoromethyl)pyridin-5-yl)-5-(4-(methylsulfonyl)- phenyl)pyridin-2-amine;MMV-048;CHEMBL2041980;MFCD28502126;5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)pyridin-3-yl]pyridin-2-amine;MMV048;GTPL9726;5-[4-(methylsulfonyl)phenyl]-6'-(trifluoromethyl)[3,3'-bipyridin]-2-amine;CS-0024613;5-(4-(Methylsulfonyl)phenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine;UNII-0Z5T00JJ10;HY-106005;5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)-3-pyridyl]pyridin-2-amine;RTJQABCNNLMCJF-UHFFFAOYSA-N
SMILES:	CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(N)N=C2)C3=CN=C(C=C3)C(F)(F)F
Formula:	C₁₈H₁₄N₃O₂F₃S
M.Wt:	393.383
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

MMV390048 is a novel potent Plasmodium PI4K inhibitor with IC50 of 28 nM against intraerythrocytic life cycle stages of P. falciparum (NF54 drug-sensitive strain); blocks all life cycle stages of the malaria parasite, exhibits full chemoprotection, delays relapse in a Plasmodium cynomolgi monkey model. Parasite Infection Phase 2 Clinical

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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