PF-05150122|CAS 1235406-03-7|DC Chemicals

Cas No.:	1235406-03-7
Chemical Name:	5-chloro-2-fluoro-4-(2-(pyridazin-4-yl)-4-(trifluoromethyl)phenoxy)-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
Synonyms:	PF05150122
SMILES:	ClC1C(OC2C=CC(C(F)(F)F)=CC=2C2C=CN=NC=2)=CC(F)=C(S(NC2SC=NN=2)(=O)=O)C=1
Formula:	C₁₉H₁₀ClF₄N₅O₃S₂
M.Wt:	531.885
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	PF-05150122 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. Pain Phase 1 Discontinued
References:	References 1. Swain NA, et al. J Med Chem. 2017 Aug 24;60(16):7029-7042. 2. Jones HM, et al. Clin Pharmacokinet. 2016 Jul;55(7):875-87. View Related Products by Target Sodium Channel Pain

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