VA-012|VA012

Cas No.:	885898-58-8
Chemical Name:	(1-Benzyl-1H-indol-3-ylmethyl)-pyridin-3-yl-amine
Synonyms:	(1-Benzyl-1H-indol-3-ylmethyl)-pyridin-3-yl-amine
SMILES:	C1=CC=C(NCC2=CN(CC3=CC=CC=C3)C3=CC=CC=C23)C=N1
Formula:	C₂₁H₁₉N₃
M.Wt:	313.396
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

VA-012 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM) that exhibits dose-dependent potentiation of 5-HT efficacy with EC50 of 16 nM; shows no significant off-target activities, and low binding competition with serotonin or other orthosteric ligands; increases the anorectic effect combined with the SSRI sertraline; reduces food intake and body weight gain without causing CNS-related malaise.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
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