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| Cas No.: | 2280037-51-4 |
| Chemical Name: | Bobcat339 |
| Synonyms: | Bobcat339;BCP31159;1-([1,1'-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one |
| SMILES: | ClC1C(N([H])[H])=NC(N(C=1[H])C1=C([H])C([H])=C([H])C(C2C([H])=C([H])C([H])=C([H])C=2[H])=C1[H])=O |
| Formula: | C16H12ClN3O |
| M.Wt: | 297.738982200623 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a; Bobcat339 is a useful tool for investigation of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription. |
| References: | 1. Chua GNL, et al. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185. View Related Products by Target DNA Methyltransferase (DNMT) |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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