MLT-747|MLT747;MLT 747

Cas No.:	2097853-86-4
Chemical Name:	MLT-747
Synonyms:	MLT-747;1-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(pyrrolidine-1-carbonyl)pyridin-3-yl]urea;CID 129117094;Urea, N-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-N'-[5-chloro-6-(1-pyrrolidinylcarbonyl)-3-pyridinyl]-;MLT747,MLT 747
SMILES:	ClC1=CC(=CN=C1C(N1CCCC1)=O)NC(NC1C=NC2=CC(=NN2C=1[C@H](C)OC)Cl)=O
Formula:	C₂₀H₂₁Cl₂N₇O₃
M.Wt:	478.331841230392
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

MLT-747 (MLT747) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 14 nM; binds MALT1 in the allosteric Trp580 pocket, reversibly binds and stabilizes human mutant MALT1-W580S in vitro and in MALT1mut/mut B cells, inhibits MALT1 peptide cleavage.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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