TES-1025 |CAS 1883602-21-8|DC Chemicals

Cas No.:	1883602-21-8
Chemical Name:	TES-1025
Synonyms:	TES-1025;2-(3-(((5-cyano-6-oxo-4-(thiophen-2-yl)-1,6-dihydropyrimidin-2-yl)thio)methyl)phenyl)acetic acid;Benzeneacetic acid, 3-[[[5-cyano-1,6-dihydro-6-oxo-4-(2-thienyl)-2-pyrimidinyl]thio]methyl]-;inhibit,Inhibitor,TES 1025,TES1025,TES-1025
SMILES:	C1(CC(O)=O)=CC=CC(CSC2NC(=O)C(C#N)=C(C3SC=CC=3)N=2)=C1
Formula:	C₁₈H₁₃N₃O₃S₂
M.Wt:	383.44412112236
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

TES-1025 (TES1025) is a potent, selective inhibitor of human ACMSD (α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase) with IC50 of 13 nM, increases NAD+ levels in cellular systems; demonstrates suitable overall balance of good physicochemical properties and in vitro safety profile; modulates intracellular NAD+ levels with consequent in vivo enhancement of de novo NAD+ biosynthesis via ACMSD target engagement.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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