Cas No.: | 331963-29-2 |
Chemical Name: | 3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide |
Synonyms: | I 2906;I2906 |
SMILES: | CCCCCCCCCCCCC(NNC(C1C(=O)N(CC)C2=CC=CC=C2C=1O)=O)=O |
Formula: | C25H37N3O4 |
M.Wt: | 443.579 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity; shows good activity against M. tuberculosis H37Ra with MIC of 0.5 ug/ml; significantlt reduces bacterial loads of both lungs and spleen in a murine model.Bacterial InfectionPreclinical |