| Cas No.: | 171009-07-7 |
| Chemical Name: | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol |
| Synonyms: | CCT018159 |
| Formula: | C20H20N2O4 |
| M.Wt: | 352.39 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | CCT-01815 is a novel potent inhibitor of Hsp90 ATPase activity with IC50 of 7.1 uM; shows a mean cellular GI50 of 5.3 uM across a panel of human cancer cell lines; causes cell cytostasis associated with a G(1) arrest and induces apoptosis, also inhibites key endothelial and tumor cell functions implicated in invasion and angiogenesis; significantly reduces transcription factor HNF4A protein levels in iPSC-derived hepatic progenitor cells. |

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