Cas No.: | 284661-68-3 |
Chemical Name: | L-Valinamide, N-[(3-fluorophenyl)methyl]glycyl-N-[(1S,2R)-3-[[(3-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-3-methyl- |
Synonyms: | DPH-153893 |
SMILES: | O=S(=O)(N(CC(C)C)CC(C(NC(=O)C(NC(=O)CNCC1C=C(F)C=CC=1)C(C)(C)C)CC1C=CC=CC=1)O)C1C=CC=C(N)C=1 |
Formula: | C35H48FN5O5S |
M.Wt: | 669.8495 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent and selective inhibitor of HIV-1 protease with IC90 of 4-40 nM; showes no loss in potency towardrecombinant mutant HIVs with the D30N mutation and a fivefold or smaller loss in potency toward mutant variants with three to five amino acid substitutions. |