Cas No.: | 93565-01-6 |
Chemical Name: | 1,4-Butanediamine, N,N'-di-2,3-butadienyl-, dihydrochloride (9CI) |
Synonyms: | MDL72527;MDL 72527 |
SMILES: | Cl.Cl.C(NCCCCNCC=C=C)C=C=C |
Formula: | C12H20N2.2HCl |
M.Wt: | 265.2 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively; significantly reduces ETBF-induced chronic inflammation and proliferation in C57BL/6 mice; also reduces ETBF-induced colon tumorigenesis in the multiple intestinal neoplasia mouse model. |