Cas No.: | 2101954-85-0 |
Chemical Name: | (2-((3-(2-(pyrrolidin-1-yl)ethyl)phenyl)amino)-1,4-phenylene)bis((4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)methanone) |
Synonyms: | EML633;EML 633 |
Formula: | C42H62N6O2 |
M.Wt: | 682.998 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity. |