Cas No.: | 41179-33-3 |
Chemical Name: | 4-(2'-fluoro-[1,1'-biphenyl]-4-yl)-N-(4-hydroxyphenyl)butanamide |
Synonyms: | CMPD 1;CMPD1 |
SMILES: | OC1=CC=C(C=C1)NC(=O)CCCC2=CC=C(C=C2)C3=C(F)C=CC=C3 |
Formula: | C22H20FNO2 |
M.Wt: | 349.4 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent, selective, non-ATP-competitive inhibitor of p38α-mediated MK2a phosphorylation with apparent Ki of 330 nM; dose not prevents p38α-mediated phosphorylation of MBP and ATF-2; induces a significant G2/M arrest, also inhibits tubulin polymerization in glioblastoma cells. |