CK-0106023| CAS 336115-72-1

Cas No.:	336115-72-1
Chemical Name:	N-1-(3-Benzyl-7-chloro-4-oxoquinazolin-2-yl)propyl-4-bromo-N-3-(dimethylamino)propylbenzamide
Synonyms:	Benzamide,4-bromo-N-[1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]propyl]-N-[3-(dimethylamino)propyl]-;N-[1-(3-BENZYL-7-CHLORO-4-OXO-3,4-DIHYDRO-QUINAZOLIN-2-YL)-PROPYL]-4-BROMO-N-(3-DIMETHYLAMINO-PROPYL)-BENZAMIDE;N-[1-(3-benzyl-7-chloro-4-oxoquinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide;Sb-743921;UNII-S38NRK3X01;MFCD10574781;DTXSID40955247;N-[1-(3-Benzyl-7-chloro-4-oxo-quinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide;CK0106023;(R)-CK 0106023;CID 11261882;Benzamide, 4-bromo-N-(1-(7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl)propyl)-N-(3-(dimethylamino)propyl)-;CK-0106023;S38NRK3X01;SCHEMBL12393608;P-CHLOROSULFONYLDIHYDROCINNAMICACID;N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide;336115-72-1;CHEMBL1164552;AKOS017343468;N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide;Q27288527
SMILES:	CCC(C1=NC2=C(C=CC(=C2)Cl)C(=O)N1CC3=CC=CC=C3)N(CCCN(C)C)C(=O)C4=CC=C(C=C4)Br
Formula:	C₃₀H₃₂N₄O₂ClBr
M.Wt:	595.95768
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent, specific, allosteric inhibitor of KSP motor domain ATPase with Ki of 12 nM; displays >200-fold selectivity over the mitotic kinesins CENP-E, MKLP1 and Kif1A; causes mitotic arrest and growth inhibition in several human tumor cell lines; exhibits antitumor activity in tumor-bearing mice.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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