Cas No.: | 81496-19-7 |
Chemical Name: | (Z)-7-((1S,2S,5R)-5-([1,1'-biphenyl]-4-ylmethoxy)-3-oxo-2-(tetrahydro-2H-pyran-4-yl)cyclopentyl)hept-4-enoic acid |
Synonyms: | AH23848;AH 23848 |
Formula: | C29H34NO5.1/2Ca |
M.Wt: | 496.6 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A dual antagonist of TP1 and EP4 receptors that inhibit TXA2-induced platelet aggregation with IC50 of 0.26 uM; impairs PGE2-mediated relaxation of piglet saphenous vein by antagonizing the PGE2 receptor EP4. |