Cas No.: | 1227675-51-5 |
Chemical Name: | 6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide |
Synonyms: | SCH-39166;SCH 39166;Ecopipam |
Formula: | C19H20ClNO.HBr |
M.Wt: | 394.73 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent, selective D1 dopamine receptor antagonist with Ki of 3.6 nM, >300-fold selectivity over D2 and 5-HT2 receptors; blocks dopamine-stimulated adenylate cyclase with Ki of 9.1 nM, inhibits both rat and squirrel monkey conditioned avoidance responding; antagonizes apomorphine-induced stereotypy in rats, demonstrates potential antipsychotic activity in vivo. |