Cas No.: | 1807453-83-3 |
Chemical Name: | (4-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl)methanamine |
Synonyms: | ND336;ND 336 |
Formula: | C16H17NO3S2.HCl |
M.Wt: | 371.9 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively; has minimal effect on other MMPs; accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition. |