Cas No.: | 423169-68-0 |
Chemical Name: | SC-57461A |
Synonyms: | SC-57461A;3-[3-(4-benzylphenoxy)propyl-methylamino]propanoic acid,hydrochloride;SC 57461A;CHEMBL543405;CTK8E8396;LS-121548;SC 57461;SC-57461;SC-57461 hydrochloride;SureCN1895851;N-Methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl β-alanine hydrochloride |
SMILES: | Cl.OC(CCN(CCCOC1C=CC(CC2C=CC=CC=2)=CC=1)C)=O |
Formula: | C20H26ClNO3 |
M.Wt: | 363.878345012665 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM), no effect on production of the cyclooxygenase metabolite thromboxane B(2); orally active in vivo.Irritable Bowel SyndromeDiscontinued |