Cas No.: | 529507-84-4 |
Chemical Name: | N4-[7-Chloro-2-[(1E)-2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-1,4-pentanediamine |
Synonyms: | XIB4035 |
Formula: | C26H31Cl2N3 |
M.Wt: | 456.45 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A nonpeptidyl small molecule agonist of GDNF family receptor α1 (GFRα-1); concentration-dependently inhibits [(125)I]GDNF binding in Neuro-2A cells with IC50 of 10.4 uM; induces autophosphorylation of Ret protein, promotes neurite outgrowth in Neuro-2A cells, and induces Ret autophosphorylation in the Neuro-2A cells. |