Cas No.: | 415687-81-9 |
Chemical Name: | 4-bromobenzaldehyde N-(2,6-dimethylphenyl)semicarbazone |
SMILES: | N(C1C(=CC=CC=1C)C)C(=O)N/N=C/C1C=CC(Br)=CC=1 |
Formula: | C16H16BrN3O |
M.Wt: | 346.22 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent anthrax lethal toxin entry inhibitor with IC50 of 1.7 uM, inhibits endosomal trafficking pathways exploited by multiple toxins and viruses; also delays lysosomal targeting and degradation of the EGF receptor, does not neutralize acidic organelles; a powerful tool for the study of membrane trafficking and represents a class of host-targeted compounds for therapeutic development to treat infectious disease. |