Cas No.: | 141136-83-6 |
Chemical Name: | Ser-Phe-Leu-Leu-Arg-Asn |
Synonyms: | L-Asparagine,L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-;SER-PHE-LEU-LEU-ARG-ASN;THROMBIN RECEPTOR ACTIVATOR FOR PEPTIDE 6 (TRAP-6);Thrombin Receptor Activator Peptide 6;TRAP-6;(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-oxobutanoic acid;Thrombin receptor (42-47), human;SFLLRN;SFLLRN-OH;BDBM85086;Thrombin Receptor Activator Peptide 6, >95% (HPLC);Ser-Phe-Leu-Leu-Arg-Asn;Thrombin Receptor Activator Peptide 6;L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine |
SMILES: | O=C([C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C([C@]([H])(C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])N([H])C([C@]([H])(C([H])([H])O[H])N([H])[H])=O)=O)N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C(N([H])[H])=O)=O)C([H])([H])C([H])([H])C([H])([H])/N=C(\N([H])[H])/N([H])[H])=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] |
Formula: | C34H56N10O9 |
M.Wt: | 748.8700 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | TRAP-6 is a protease-activated receptor 1 (PAR1) agonist. Sequence: Ser-Phe-Leu-Leu-Arg-Asn. |
References: | [1]. Tripathi T, et al. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014 May 29;55(6):3912-21. |