Cas No.: | 231957-54-3 |
Chemical Name: | N-(5-Cyano-2-pyridinyl)-N'-[(1S,2S)-2-[6-fluoro-2-hydroxy-3-(1-oxopropyl)phenyl]cyclopropyl]urea |
Synonyms: | PC-815;MIV150 |
Formula: | C19H17FN4O3 |
M.Wt: | 368.4 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A high-affinity, allosteric HIV-1 and HIV-2 reverse transcriptase inhibitor (NNRTI) with EC50 of 1 nM; possesses poor oral bioavailability, and demonstrates efficacy when formulated as a topical microbicide (PC-815: Carrageenan gel formulation).HIV InfectionPhase 1 Clinical |