Cas No.: | 174847-98-4 |
Chemical Name: | (3R,4S)-3-Hydroxy-4-[[8-[[(3β)-3-hydroxy-28-oxolup-20(29)-en-28-yl]amino]-1-oxooctyl]amino]-6-methylheptanoic acid |
Synonyms: | IC9564;AIDS033640 |
Formula: | C46H78N2O6 |
M.Wt: | 755.138 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | IC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor that blocks HIV-1 envelope-mediated membrane fusion with IC90 of 0.22 uM for NL4-3 strain; also has IC90s of >5, 2.65, and 1.84 uM for DH012, QZ4734, and HIV-1 89.6, respectively; HIV-1 gp120 plays a key role in the anti-HIV-1 activity of IC9564. |