Cas No.: | 1380336-17-3 |
Chemical Name: | N1-(((R)-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl)-N1-((S)-5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine |
Formula: | C23H32N4 |
M.Wt: | 364.537 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | TIQ-15 is a potent and selective CXCR4 antagonist, inhibits attachment of X4 HIV-1IIIB virus in MAGI-CCR5/CXCR4 cells with IC50 of 3 nM; inhibits calcium release in Chem-1 cells with IC50 of 3 nM, shows no cross-activity in a panel of chemokine receptor assays in both CXCR and CCR types; |