Cas No.: | 2089059-30-1 |
Chemical Name: | (1R,5R)-2-benzyl-N-phenyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[c]azepin-8-amine |
Synonyms: | JVW 1009;JVW1009 |
Formula: | C24H24N2 |
M.Wt: | 340.47 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively; reduces neurodegeneration in C. elegans model of amyloid precursor protein-mediated neurodegeneration. |