S-18986| CAS 175340-20-2

Cas No.:	175340-20-2
Chemical Name:	S 18986
Synonyms:	S 18986;(3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide;S-18986;(S)-2,3-dihydro-(3,4)cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide;2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide;AC1LCV4Z;CHEMBL320642;DCL001120;S18986-1;SureCN6622911;1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-
SMILES:	C1=CC=C2C(=C1)N3CCC[C@@H]3NS2(=O)=O
Formula:	C₁₀H₁₂N₂O₂S
M.Wt:	224.27948
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

S-18986 is an orally bioavailable and BBB penetrant positive allosteric modulator of AMPA receptors; has nootropic and neuroprotective effects in animal studies, and induces both production of BDNF and AMPA-mediated release of noradrenaline and acetylcholine in the hippocampus and frontal cortex of the brain.

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