Cas No.: | 1229591-56-3 |
Chemical Name: | 2-Amino-5,6,7,8-tetrahydro-4-methyl-7-(1-naphthalenyl)-5-oxo-4H-1-benzopyran-3-carbonitrile |
Synonyms: | UCPH102 |
Formula: | C21H18N2O2 |
M.Wt: | 330.387 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | UCPH-102 is a selective, brain penetrant inhibitor of EAAT1 (Excitatory amino acid transporter 1) with IC50 of 420 nM; exhibits no inhibitory activity aganist EAAT2-5 (>300 uM); has been shown to cross the blood-brain barrier, and become a valuable tool for studying the role of EAAT1 in brain. |