Cas No.: | 1883548-88-6 |
Chemical Name: | 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride |
Synonyms: | FFN206 |
Formula: | C12H16Cl2N2O2 |
M.Wt: | 291.172 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles; the apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine; an useful tool for optical examination of VMAT2 function in cell culture. |