LUF7346| CAS 1821638-40-7

Cas No.:	1821638-40-7
Chemical Name:	2-[4-(2-Bromo-benzoyl)-phenoxy]-N-pyridin-3-yl-acetamide
Synonyms:	LUF7346;2-[4-(2-Bromo-benzoyl)-phenoxy]-N-pyridin-3-yl-acetamide;BDBM50499725;LUF7346, >=98% (HPLC);2-[4-(2-Bromobenzoyl)phenoxy]-N-(pyridin-3-yl)acetamide
SMILES:	BrC1C=CC=CC=1C(C1C=CC(=CC=1)OCC(NC1C=NC=CC=1)=O)=O
Formula:	C₂₀H₁₅BrN₂O₃
M.Wt:	411.248704195023
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

LUF7346 is a novel hERG allosteric modulator that slows IKr deactivation and positively shifting IKr inactivation; rescues the genetic form of LQTS, reverses drug-induced LQTS and correct thes combination of genetic and drug-induced LQTS; normalises both action- and field potentials (AP and FP, respectively) in all hPSC-CMs by slowing IKr deactivation and positively shifting the IKr inactivation.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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